When the San Francisco 49ers traded for Brian Robinson Jr., it effectively ended any hope for Isaac Guerendo becoming the No.

The Seattle Seahawks will host the rival San Francisco 49ers in the season opener in an early NFC West matchup.

The Arizona Cardinals lost to the San Francisco 49ers on Sunday, Dec. 17 at State Farm Stadium. Look back at our live coverage from the game. Arizona Cardinals no match for Brock Purdy, Christian ...

Jauan Jennings is back practicing with the San Francisco 49ers after being out for the last month with a calf injury.

Jauan Jennings, aformer Tennessee wide receiver, inked a new deal with the San Francisco 49ers ahead of the 2025 season.

Arizona Cardinals no match for Brock Purdy, Christian McCaffrey, 49ers The Arizona Cardinals scored a late touchdown to make it 45-29 49ers, but the game was over long before that.

Seattle Seahawks vs San Francisco 49ers picks, predictions, odds, win probabilities for NFL Week 1 Sunday football game on Sept. 7. Who will win game?

The Cardinals have historically given Kyle Shanahan's 49ers trouble, so they're a dangerous opponent despite their 2022 struggles.

In a day of jarring futility, the most symbolic image of the 49ers’ defensive performance is one Dre Kirkpatrick will want to forget. The 10-year veteran, who started 11 games for Arizona last ...