RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...

Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other’s binding to DNA in fission yeast. They found that ...

The study, authored by Tripti Midha, Anatoly Kolomeisky and Oleg Igoshin and published in the Proceedings of the National Academy of Sciences. Every living cell must interpret its genetic code — a ...

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...