Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular ...

A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Scientists studying thousands of rats discovered that gut bacteria are shaped by both personal genetics and the genetics of ...

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats ...

If something similar occurs in humans, and given growing evidence that the gut microbiome matters for health, genetic influence on human health may be underestimated in large studies; genes may affect ...