Hemochromatosis is one of the most common genetic conditions and can be life-threatening — here's how it manifests.

Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload.

Discover which foods and strategies actually boost iron status and why the right dose and pairing can make the difference ...

Expert Rev Mol Diagn. 2010;10(6):755-763. The diagnosis is based on a three-step strategy. The first step is recognizing clinical signs and symptoms. Many symptoms in various combinations may suggest ...

Iron overload, characterized by elevated serum ferritin levels, has long been associated with various systemic complications, yet its impact on skeletal health has not been as well understood. A ...

Merganser Biotech, a drug licensing and development startup, has secured funding from a consortium that includes BioAdvance, the Biotechnology Greenhouse of Southeastern Pennsylvania and individual ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

Iron overload syndrome, including hereditary hemochromatosis, is a disorder marked by excessive iron buildup in the body, primarily due to HFE gene mutations or secondary causes like chronic ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

When you take iron can affect how well it works. Here, experts explain the best time to take iron supplements to maximize absorption and reap the benefits.

Iron is usually seen as your ally in pregnancy, but what happens when your body gets more than it needs? Iron overload is a condition where excess iron builds up in organs like the liver, heart, and ...

Rhino horns may be the key to saving the endangered species from a potentially fatal condition: iron overload disorder. With the species dwindling in number, if zookeepers were alerted to the ...