Coordination of microtubules and the actin cytoskeleton is important in several types of cell movement. mDia1 is a member of the formin-homology family of proteins and an effector of the small GTPase ...

Cytoplasmic streaming is the persistent circulation of the fluid contents of large eukaryotic cells, driven by the action of molecular motors moving along cytoskeletal filaments, entraining fluid.

Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare ...

Plant growth and development are a genetically predetermined series of events but can change dramatically in response to environmental stimuli, involving perpetual pattern formation and reprogramming ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...

Researchers have developed photoresponsive derivatives of the anticancer drug Taxol®, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell ...

Huntington’s disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

A KAIST research team has discovered that the Huntington protein originally plays a critical role in forming the neuronal cytoskeleton under normal conditions. The findings were published in the ...