Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.
Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through ...
Their results, published online on July 16 in the journal Life Science Alliance, describe a novel role for hnRNP E1 in binding DNA in the nucleus. We found that this RNA binding protein not only has ...
This is a preview. Log in through your library . Abstract The small GTPase rab5 has been shown to represent a key regulator in the endocytic pathway of mammalian cells. Using a PCR approach to ...
Trafficking and stabilization of AMPA receptors at synapses in response to cocaine exposure is thought to be critical for expression of cocaine addiction and relapse. Glutamate receptor-interacting ...
This is a preview. Log in through your library . Abstract Proinflammatory responses induced by Toll-like receptors (TLRs) are dependent on the activation of the NF-ĸB and mitogen-activated protein ...
RNA turnover in the nuclei of eukaryotic cells is controlled by the RNA exosome aided by numerous cofactors. Researchers at now show how two major nuclear exosome cofactors recognize their RNA targets ...
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