A large U.S. randomized trial published in the New England Journal of Medicine found that etomidate, compared with ketamine, ...

Xylazine is a sedative that's only approved for use in animals, but now it is showing up in illegal street drugs up and down the East Coast. WBUR's Martha Bebinger reports that it may be contributing ...

Sedative-, hypnotic-, or anxiolytic- (SHA-) related disorders include SHA intoxication, SHA withdrawal, and SHA-use disorder. These disorders result from abuse of a class of medications known as ...

It extends the feeling of an opiate high. It's hard to detect and can't be reversed by medications like Narcan. It's immediately recognizable by the gruesome, scaly wounds that emerge on users' skin, ...

A powerful veterinary sedative called medetomidine was found in two drug samples collected following a mass overdose earlier this month in Baltimore's Penn North community, Baltimore City Health ...

Melatonin is a popular sleep aid. And as an ER doctor, it’s the one I get asked about the most. Melatonin is easily the subject of more myths and questions than perhaps any other supplement. Melatonin ...

Inhaled isoflurane sedation was on par with IV midazolam for children age 3 to 17 years in the ICU on mechanical ventilation in a randomized trial. Isoflurane also reduced time to extubation and ...

Benzodiazepines, opioid analgesics, and other sedatives have indispensable medical uses; however, they can also stimulate the reward center in the brain. In susceptible individuals, this can lead to ...

The life-threatening drug, medetomidine, has been found in 457 drug seizures in the third quarter of this year, a surge from ...

There’s a new beast on the streets — and it’s nothing to bark at. A powerful animal tranquilizer is increasingly saturating the US drug supply, fueling mass overdose outbreaks in hot spots like ...

Medetomidine, a veterinary sedative, mixed into fentanyl has sent thousands to hospitals, not only for overdose but for life-threatening withdrawal. It is spreading to other cities.