MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological ...

Dysfunctional mitochondria are a hallmark of T cell ageing and contribute to organismal ageing. This arises from the accumulation of reactive oxygen species (ROS), impaired mitoch ...

The body has an intricate system to defend against infections where each type of immune cell plays a distinct role. Now, a ...

Researchers at MUSC Hollings Cancer Center have discovered a potentially powerful weapon in the fight against head and neck ...

CAMBRIDGE, MA. & ROCKVILLE, MD.--(BUSINESS WIRE)--Clasp Therapeutics, a biotechnology company bringing unparalleled precision to immuno-oncology using next-generation TCEs, today announced new data ...

Short-term IF boosts glucose homeostasis, but prolonged fasting in adolescence may impair β cell maturation—potentially linking chronic IF to type 1 diabetes risk. Study: Chronic intermittent fasting ...

New preclinical findings highlight Telomir-1's ability to reverse CDKN2A gene silencing by DNA methylation, reactivating this gene - often called the body's natural "cell cycle brake." These results ...