An international study led by the University of Basel has discovered that nuclear pore complexes—tiny gateways in the nuclear membrane—are not rigid or gel-like as once thought. Their interiors are ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Just as life pulsates in big vibrant cities, it also prospers in crowded environments inside cells. The interior of cells is densely packed with biomolecules like proteins and nucleic acids. How is ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings ...

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life. Each of us starts ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...