How pollution and the microbiome interact with Tregs, the immune system regulators whose discovery was honored with the Nobel Prize

Researchers are gaining insights into how external factors like air pollutants, diet and medications, and even microbes in ...

How does your immune system stay balanced? A Nobel Prize-winning answer

Regulatory T cells help your immune system distinguish between ‘self’ and ‘nonself’ – and can open doors to better treatments ...
Nature

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

Sped-up evolution may help bacteria take hold in gut microbiome

Everywhere you go, you carry a population of microbes in your gastrointestinal tract that outnumber the human cells making up ...
eLife

Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...